thematique : EDISS

Thèse :Enabling local immune modulation using gene-based nanomedicine for the treatment of Inflammatory Bowel Diseases

Keywords: Nanocarriers, nucleic acid, physico-chemical characterization, oral administration, in vivo studies Aim of the thesis: The aim of the thesis project is to develop a multifunctional therapeutic system that will enable oral delivery of oligonucleotides for the treatment of inflammatory bowel pathologies. A translation approach to develop innovative hydrogel-doped nanoparticle platform and to evaluate their...

Post-Doc : Design and development of gene delivery systems for oral route

Supervisors: Dr. Giovanna Lollo Keywords: Nanocarriers, nucleic acid, physico–chemical characterization, oral administration, in vivo studies Starting date: January 2022 (12–18 months) Laboratory: The LAGEPP (https://lagepp.univ–lyon1.fr/en/home/) is a research laboratory of the University Lyon 1 and the French national Institute for scientific research (CNRS UMR 5007). It develops pluridisciplinary research in chemical engineering, pharmaceutical engineering and...

Bis(monoacylglycerol)phosphate, a putative regulator of Leishmania virulence towards macrophages

Directrice de thèse: Isabelle Delton, isabelle.delton@insa-lyon.fr Co-encadrants : Céline Costaz, celine.costaz@insa-lyon.fr, Samira Azzouz-Maache, samira.azzouz-maache@univ-lyon1.fr Le sujet en version PDF. Leishmaniases are a complex of tropical and sub-tropical human diseases caused by unicellular parasites of the genus Leishmania transmitted by a sand-fly vector and displaying various clinical expressions. Nearly 350 million people are exposed to leishmaniases...

Synthèse et caractérisation de particules de polymères iodés et utilisation comme agent de contraste pour l’observation par scanner spectral

Name: Joëlle BALEGAMIRE Graduate School:  Ecole Doctorale de Chimie de l’Université de Lyon Directors: Yves CHEVALIER et Hatem FESSI Beginning of the thesis: 15/01/2016 Expected end of the thesis: 15/01/2019 (3ans) Funding: Thèse EuropéenneNom : Joëlle BALEGAMIRE Ecole doctorale : Ecole Doctorale de Chimie de l’Université de Lyon Directeurs : Yves CHEVALIER et Hatem FESSI Début...

Nouvelle approche de vectorisation ciblant les macrophages en vue d’immunothérapie anti-tumorale

Titre : Nouvelle approche de vectorisation ciblant les macrophages en vue d’immunothérapie anti-tumorale Etudiant : Sabrina NICOLAS Ecole doctorale : EDISS Directeur de thèse: BOLZINGER Marie-Alexandrine (Pr) Co-encadrants : FESSI Hatem (PR), BOURGEOIS Sandrine (MCU) et ALMOUAZEN Eyad (MCU) Début thèse : 1.10.2015 Fin de thèse prévu : 30.09.2018 Titre : Nouvelle approche de vectorisation...